ǂThe ǂimpact of oral changes and symptoms on the quality of life of patients with primary Sjogrens syndrome

[S. A. Vujović Ristić]

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Uvod: Primarni Sjegrenov sindrom je autoimuno oboljenje koje se klinički odlikuje suvoćom usne duplje i očiju a promene su prisutne i na drugim organima. Različit spektar simptoma i komplikacija čini primarni Sjegrenov sindrom kompleksnim oboljenjem koje u značajnoj meri utiče na kvalitet života. Cilj: Utvrditi da li su oralne promene i simptomi faktor koji značajno utiče na parametre kvaliteta života povezanog sa zdravljem ispitanika sa primarnim Sjegrenovim sindromom. Materijal i metod: Istraživanje je realizovano kao klinička opservaciona studija, po dizajnu slučaj - kontrola. Uključeno je 80 ispitanika sa dijagnozom primarnog Sjegrenovog sindroma, podeljenih u dve grupe, na osnovu oralnog statusa. Detaljno su analizirani: kvalitet života povezan sa zdravljem, oralni status svih ispitanika, stanje potpornog aparata zuba, nivo njihove oralne higijene i navike vezane za oralno zdravlje. Pored toga, izvršeni su prevod, transkulturološka adaptacija i procena psihometrijskih karakteristika specifičnog upitnika za procenu kvaliteta života pacijenata sa primarnim Sjegrenovim sindromom (PSS-QoL). Rezultati: Ispitanici sa oralnim promenama i simptomima imaju lošiji kvalitet života u odnosu na ispitanike kod kojih ove manifestacije nisu zabeležene. Srpska verzija PSS-QoL upitnika pokazala je zadovoljavajuće psihometrijske osobine. Zaključak: Oralne promene i simptomi kod ispitanika sa primarnim Sjegrenovim sindromom značajno su udruženi sa smanjenjem kvaliteta njihovog života. Multidisciplinarni pristup u lečenju, koji obuhvata kontinuiranu stomatološku zaštitu, neophodan je radi postizanja boljeg oralnog zdravlja i unapređenja kvaliteta života ove populacije.

Introduction: Primary Sjogren's syndrome is an autoimmune disease that is clinically characterized by dryness of the oral cavity and eyes. It also affects other organs. A diverse range of symptoms and complications makes primary Sjogren's syndrome a complex disease that significantly impairs the patient’s quality of life. Aim: To determine whether oral changes and symptoms are an important factor that affects the health-related quality of life of subjects with primary Sjögren's syndrome. Material and method: The research was carried out as a clinical observational study, with a case-control design. Eighty subjects diagnosed with primary Sjögren's syndrome were included, and divided into two groups based on oral status. The following were analyzed: the health-related quality of life, the oral health of all subjects, their periodontal status, the level of their oral hygiene and habits related to oral health. Translation, transcultural adaptation and evaluation of psychometric characteristics of a specific health-related quality of life questionnaire designed for primary Sjögren's syndrome (PSS-QoL) were performed. Results: Subjects with oral changes and symptoms have a worse health-related quality of life compared to subjects in whom these manifestations were not recorded. The Serbian version of the PSS-QoL questionnaire showed satisfactory psychometric properties. Conclusion: Oral changes and symptoms in subjects with primary Sjögren's syndrome are significantly associated with a decrease in their quality of life. A multidisciplinary approach to treatment, which includes continuous dental care, is necessary to achieve better oral health and improve the quality of life of this population.

primarni Sjegrenov sindrom, oralne promene, kvalitet života povezan sa zdravljem.

primary Sjögren's syndrome, oral manifestations, health-related quality of life.

616.314(043.3)

Stomatologija, Farmakologija

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