Title
Uticaj lekova na nivo TSH kod pacijenata na supstitucionoj terapiji tiroksinom
Creator
Anđelković, Marija, 1977-
Copyright date
2013
Object Links
Select license
Autorstvo-Nekomercijalno 3.0 Srbija (CC BY-NC 3.0)
License description
Dozvoljavate umnožavanje, distribuciju i javno saopštavanje dela, i prerade, ako se navede ime autora na način odredjen od strane autora ili davaoca licence. Ova licenca ne dozvoljava komercijalnu upotrebu dela. Osnovni opis Licence: http://creativecommons.org/licenses/by-nc/3.0/rs/deed.sr_LATN Sadržaj ugovora u celini: http://creativecommons.org/licenses/by-nc/3.0/rs/legalcode.sr-Latn
Language
Serbian
Cobiss-ID
Inventory ID
D-2652
Theses Type
Doktorska disertacija
Other responsibilities
mentor
Folić, Marko, 1979-
član komisije
Janković, Slobodan, 1961-
član komisije
Đukić, Aleksandar, 1967-
član komisije
Šumarac-Dumanović, Mirjana, 1960-
Academic Expertise
Medicinske nauke
University
Univerzitet u Kragujevcu
Faculty
Fakultet medicinskih nauka
Alternative title
The impact of drugs on TSH level of patients’ using levothyroxin replacement therapy
Publisher
Kragujevac : [M. Anđelković],
Format
PDF/A (111 listova)
description
datum odbrane: 14.01.2014.
Abstract (en)
Hypothyroidism requires thyroxine replacement, regardlesss
thyroidectomy was performed or not. The goal of this research
was to determine how different groups of drugs – ACE inhibitors,
selective beta blockators, Ca antagonists, nitrates, statins, or
different combinations of these drugs affect TSH level at the
patients on the thyroxine replacement therapy after total
thyroidectomy. Research took place in 2012 and was performed
on the outpatients that check their chormones at Department of
Nuclear Medicine in Clinical Center Kragujevac. 247 patients
were divided into groups depending on which drugs they had
been prescribed. The control group involved patients taking just
thyroxine without other medication. TSH level of patients in
control group was compared with TSH level of patients in groups
taking other drugs. Our study showed that patients that use
selective beta bloskators have significantly higher level of TSH
than patients that don’t take these drugs. TSH level in the grops
of patients using all other drugs did not differ from the control
group.
Abstract (sr)
Hipotireoidizam zahteva korišćenje supstitucione terapije tiroksinom, bez obzira da li je štitasta žlezda prisutna ili je izvršena tiroidektomija. Cilj ovog
istraživanja bio je da se utvrdi kako pojedini lekovi – ASE inhibitori, selektivni beta blokatori, Sa antagonisti, nitrati, statini, ili njihove kombinacije utiču na nivo TSH kod pacijenata na supstituciji tiroksinom nakon totalne tireoidektomije. Ispitivanje je sprovedeno tokom 2012. godine na ambulantnim pacijentima koji hormone kontrolišu u Centru za nuklearnu medicinu KC Kragujevac.247 pacijenata je podeljeno u grupe u zavisnosti PRILOG 102 od lekova koje koriste. . Kontrolu su činili pacijenti koji imaju u terapiji samo tiroksin. Upoređivni su nivoi TSH
kontrolne i ispitivanih grupa. Pokazano je da pacijenti koji koriste selektivne beta blokatore imaju značajno viši nivo TSH od pacijenata koji nemaju te lekove u terapiji, dok se TSH pacijenata koji su koristili ostale lekove ne
razlikuje od kontrolne grupe.
Authors Key words
levotiroksin,interakcija lekova, ACE inhibitori, selektivni beta blokatori, Ca antagonisti, nitrarti, statini, TSH
Classification
616.441-085:615.25(043.3)
Subject
Štitna žlezda - Terapija
Type
monograph
manuscript text - theses
Text
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