Title
Morfologija, imunohistohemija i polni dimorfizam neurona srednje veličine sa spinama, u nucleus accumbens čoveka
Creator
Sazdanović, Maja, 1974-
Copyright date
2012
Object Links
Select license
Bez licence - direktna primena zakona
License description
Ako ne izaberete neku od licenci, vaše zaštićeno delo može biti korišćeno samo u okviru opštih ograničenja autorskih prava. Na taj način ne dozvoljavate komercijalno ni nekomercijalno korišćenje, naročito reprodukciju, distribuciju, emitovanje, dostupnost i obradu dela. Izbor Creative Commons (CC) licence promoviše diseminaciju vašeg dela. Za više informacija: http://creativecommons.org.rs/licence
Language
Serbian
Cobiss-ID
Inventory ID
D-2569
Theses Type
PhD thesis
description
datum odbrane: 26.12.2012.
Other responsibilities
mentor
Toševski, Jovo, 1947- (ths, code: 07223)
član komisije
Knežević, Milan, 1952- (oth, code: 07159)
član komisije
Tončev, Gordana, 1956- (oth, code: 07221)
član komisije
Maliković, Aleksandar, 1965- (oth, code: 02556)
Academic Expertise
Medicinske nauke
University
Univerzitet u Kragujevcu
Faculty
Fakultet medicinskih nauka
Alternative title
Morphology, immunochistochemistry and sex dimorfism medium
spiny neurons of human nucleus accumbens
Publisher
Крагујевац : [М. Саздановић],
Format
PDF/A (listova)
description
Umnoženo za odbranu.
Univerzitet u Kragujevcu, Fakultet medicinskih nauka, 20121226, dr medicinskih nauka, histologija i embriologija / neuronauke.
Bibliografija: listovi 116-142.
Izvod ; Abstract.
Abstract (en)
Nucleus accumbens is a part of the ventral striatum also known as a drug
active brain region, especially related with drug addiction. The aim of the
study was to investigate the Golgi morphology of the nucleus accumbens
neurons.
The study was performed on the frontal and sagittal sections of 15 human
brains by the Golgi Kopsch method. We classified neurons in the human nucleus accumbens according to their morphology and size into four types:
type I – fusiform neurons; type II – fusiform neurons with lateral dendrite,
arising from a part of the cell body; type III – pyramidal-like neuron; type
IV – multipolar neuron. The medium spiny neurons, which are mostly noted
regarding to the drug addictive conditions of the brain, correspond to the
type IV – multipolar neurons. Two regions of human nucleus accumbens
could be clearly recognized on Nissl and Golgi preparations each containing
different predominant neuronal types. Central part of nucleus accumbens,
core region, has a low density of impregnated neurons with predominant
type III, pyramidal-like neurons, with spines on secondary branches and rare
type IV, multipolar neurons. Contrary to the core, peripheral region, shell of
nucleus, has a high density of impregnated neurons predominantly contained
of type I and type IV – multipolar neurons, which all are rich in spines on
secondary and tertiary dendritic branches. Our results indicate great
morphological variability of human nucleus accumbens neurons.
Authors Key words
nucleus accumbens, neuroni, morfologija, bolesti
Authors Key words
nucleus accumbens
Classification
neuroni
Subject
Golgi morfologija
Subject
bolesti zavisnosti
Type
monograph
manuscript text - theses
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